p.148 抽出テキスト

れていない,がん疼痛(神経障害性疼痛,骨転移による痛み)のある患者に対して,鎮痛補助薬として抗痙攣薬,ガバペンチノイドの併用を条件付きで推奨する。

【引用文献】1) Dou Z, Jiang, Zhong J. Efficacy and safety of pregabalin in patients with neuropathic cancer pain undergoing morphine therapy. Asia Pac J Clin Oncol 2017;13:e57‒64 2) Chen DL, Li YH, Wang ZJ, et al. The research on long‒term clinical effects and patients’satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. Medicine (Baltimore)2016;95:e5144 3) Garassino MC, Piva S, Verde NL, et al. Randomised phase II trial(NCT00637975)evaluating activity and toxicity of two different escalating strategies for pregabalin and oxycodone combination therapy for neuropathic pain in cancer patients. PLoS One 2013;8:e59981 4) Mercadante S, Porzio G, Aielli F, et al. The effects of low doses of pregabalin on morphine analgesia in advanced cancer patients. Clin J Pain 2013;29:15‒9 5) Sjölund KF, Yang R, Lee KH, et al. Randomized study of pregabalin in patients with cancer‒ induced bone pain. Pain Ther 2013;2:37‒48 6) Keskinbora K, Pekel AF, Aydinli I. Gabapentin and an opioid combination versus opioid alone for the management of neuropathic cancer pain:a randomized open trial. J Pain Symptom Manage 2007;34:183‒9 7) Caraceni A, Zecca E, Bonezzi C, et al. Gabapentin for neuropathic cancer pain:a randomized controlled trial from the Gabapentin Cancer Pain Study Group. J Clin Oncol 2004;22:2909‒17 8) Yajnik S, Singh GP, Singh G, et al. Phenytoin as a coanalgesic in cancer pain. J Pain Symptom

Manage 1992;7:209‒13 III章推奨