p.197 抽出テキスト

III章推奨

既存のガイドラインとの整合性EAPCのガイドライン(2001b)では、他の原因の鑑別、オピオイドの減量を検討した後に、投与経路の変更を推奨している。

(松本禎久、小笠原利枝、川村三希子)

【文 献】臨床疑問37 1)McNicol E, Horowicz-Mehler N, Fisk RA, et al. Management of opioid side effects in cancer-related and chronic noncancer pain: A systematic review. J Pain 2003; 4: 231-56 2)Breitbart W, Marotta R, Platt MM, et al. A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients. Am J Psychiatry 1996; 153: 231-7 3)Jackson KC, Lipman AG. Drug therapy for delirium in terminally ill patients. Cochrane Database Syst Rev 2004(2): CD004770 4)Lonergan E, Britton AM, Luxenberg J, Wyller T. Antipsychotics for delirium. Cochrane Database Syst Rev 2007(2): CD005594 5)Lonergan E, Luxenberg J, Areosa Sastre A et al. Benzodiazepines for delirium. Cochrane Database Syst Rev 2004

臨床疑問38 6)Quigley C. Opioid switching to improve pain relief and drug tolerability. Cochrane Database Syst Rev 2004 7)Mercadante S, Bruera E. Opioid switching: a systematic and critical review. Cancer Treat Rev 2006; 32: 304-15 8)Morita T, Takigawa C, Onishi H, et al; Japan Pain, Rehabilitation, Palliative Medicine, and PsychoOncology(PRPP)Study Group. Opioid rotation from morphine to fentanyl in delirious cancer patients: an open-label trial. J Pain Symptom Manage 2005; 30: 96-103 9)Gagnon B, Bielech M, Watanabe S, et al. The use of intermittent subcutaneous injections of oxycodone for opioid rotation in patients with cancer pain. Support Care Cancer 1999; 7: 265-70 10)Maddocks I, Somogyi A, Abbott F, et al. Attenuation of morphine-induced delirium in palliative care by substitution with infusion of oxycodone. J Pain Symptom Manage 1996; 12: 182-9 11)Ashby MA, Martin P, Jackson KA. Opioid substitution to reduce adverse effects in cancer pain management. Med J Aust 1999; 170: 68-71 12)McNamara P. Opioid switching from morphine to transdermal fentanyl for toxicity reduction in palliative care. Palliat Med 2002; 16: 425-34

臨床疑問39 13)Enting RH, Oldenmenger WH, van der Rijt CC, et al. A prospective study evaluating the response of patients with unrelieved cancer pain to parenteral opioids. Cancer 2002; 94: 3049-56

【参考文献】臨床疑問37 14) せん妄の治療指針, 日本総合病院精神医学会 編, 星和書店, 2005