p.190 抽出テキスト

patients receiving opioids for cancer pain: a pilot study. J Clin Oncol 2003; 21: 4439-43 6)Mercadante S, Serretta R, Casuccio A. Effects of caffeine as an adjuvant to morphine in advanced cancer patients. A randomized, double-blind, placebo-controlled, crossover study. J Pain Symptom Manage 2001; 21: 369-72

臨床疑問34 7)Quigley C. Opioid switching to improve pain relief and drug tolerability. Cochrane Database Syst Rev. 2004(3): CD004847 8)Mercadante S, Bruera E. Opioid switching: a systematic and critical review. Cancer Treat Rev 2006; 32: 304-15 9)Narabayashi M, Saijo Y, Takenoshita S, et al; Advisory Committee for Oxycodone Study. Opioid rotation from oral morphine to oral oxycodone in cancer patients with intolerable adverse effects: an open-label trial. Jpn J Clin Oncol 2008; 38: 296-304 10)McNamara P. Opioid switching from morphine to transdermal fentanyl for toxicity reduction in palliative care. Palliat Med 2002; 16: 425-34 11)Ashby MA, Martin P, Jackson KA. Opioid substitution to reduce adverse effects in cancer pain management. Med J Aust 1999; 170: 68-71

臨床疑問35 12)Enting RH, Oldenmenger WH, van der Rijt CC, et al. A prospective study evaluating the response of patients with unrelieved cancer pain to parenteral opioids. Cancer 2002; 94: 3049-56

【参考文献】
臨床疑問33 13)Homsi J, Walsh D, Nelson KA. Psychostimulants in supportive care. Support Care Cancer 2000; 8: 385-97 14)宮澤真帆,郡由起子,赤穂理絵,他.オピオイド・鎮痛補助薬に起因する,がん患者の眠気に対するペモリンの有効性と安全性の検討.第14回日本緩和医療学会総会.2009