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Elevated troponin Admit to ward (Class I) See inpatient algorithmc Outpatient follow-up Patient with symptoms and signsa of myocarditis presenting to the outpatient clinic First-line assessment with history, physical examination, ECG, transthoracic echocardiography, laboratory assessmentb (Class I) Outpatient treatment Cardiovascular magnetic resonancee (Class I) Refer to hospital Obstructive CADd Treat CAD See inpatient algorithmc Low risk Diagnosis Complete risk classificationg Further work-up Further assessmentf Possible Rejected/unlikely Definitive Intermediate risk High risk Figure 6 Diagnostic algorithm and triage for outpatient myocarditis. CAD, coronary artery disease; CRP, C-reactive protein; ECG, electrocardiogram; N, no; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; Y, yes. aSee Table 6. bLaboratory testing including troponin, NT-proBNP, C-reactive protein, differential blood count. cSee Figure 5. dInvasive coronary angiography or computed tomography angiography depending on clinical likelihood/probability. eDepending on clinical situation (heart failure, arrhythmias) admit to ward. fSee Table 9. gSee Table 7. ESC Guidelines 3969 Downloaded from academic.oup.com/eurheartj/article/46/40/3952/8234483 by guest on 07 October 2026