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N Patient centred care Normal Abnormal ≥10% <5% 5% – <10% Age <40 years, resistant hypertension, suggestive signs and/or symptoms Targeted secondary hypertension treatment Screen for secondary hypertension (Class I) Calculate SCORE2/ SCORE2-OP (Class I) Assess risk modifiers (Class IIa) Consider risk tools (Class IIb) Age ≥85 years, moderate-to-severe frailty, symptomatic OH, short life expectancy Established CVD, moderate-to-severe CKD, hypertension-mediated organ damage, diabetes mellitusa, familial hypercholesterolaemia Y N N N Y Y Y Non-elevated BP Office SBP <120 mmHg and DBP <70 mmHg Elevated BP Office SBP 120–139 mmHg and/or DBP 70–89 mmHg Hypertension Office SBP ≥140 mmHg and/or DBP ≥90 mmHg ABPM / HBPM preferred over office BP Target SBP 120–129 mmHg (Class I) Target DBP 70–79 mmHg (Class IIb) Screen BP opportunistically Lifestyle measures Drug treatment for confirmed BP ≥130/80 mmHg Monitor BP and medication toleranceb Screening for hypertension Opportunistic: every 3 years <40 years; every year ≥40 years HBPM/ABPM or repeated standardized office BP Confirming hypertension Lifestyle measures Figure 19 Central Illustration. ABPM, ambulatory blood pressure monitoring; BP, blood pressure; CVD, cardiovascular disease; CKD, chronic kidney disease; DBP, diastolic blood pressure; HBPM, home blood pressure monitoring; OH, orthostatic hypotension; SBP, systolic blood pressure; SCORE2, Systematic COronary Risk Evaluation 2; SCORE2-OP, Systematic COronary Risk Evaluation 2–Older Persons. Summary algorithm for BP classification and management. See Section 5 for recommendations on out-of-office confirmation of the three BP categories. aAdults with type 2 diabetes mellitus only and younger than 60 years should be considered for SCORE2-Diabetes assessment. bThough scientific data demonstrate that, under research conditions, the optimal target BP is ≤120/70 mmHg, the target BP recommended by these guidelines in routine practice is 120–129/70–79 mmHg. If achieving this target is not possible, or if treatment is not well tolerated, then BP should be treated to as low as reasonably achievable. For persons with elevated BP, treatment with lifestyle measures for 3 months is first recommended, prior to considering medications. ESC Guidelines 3961 Downloaded from academic.oup.com/eurheartj/article/45/38/3912/7741010 by guest on 07 October 2026