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ISCHEMIA Initial Invasive or Conservative Strategy for Stable Coronary Disease (trial) ISR In-stent restenosis ISTH International Society on Thrombosis and Haemostasis IVUS Intravascular ultrasound LAD Left anterior descending LBBB Left bundle branch block LDL-C Low-density lipoprotein cholesterol LGE Late gadolinium enhancement LIMA Left internal mammary artery LITA Left internal thoracic artery LMCA Left main coronary artery LMCAD Left main coronary artery disease LODOCO2 LOw-DOse COlchicine 2 LOE Level of evidence LV Left ventricular LVEF Left ventricular ejection fraction MACCE Major adverse cardiac or cerebrovascular events MACE Major adverse cardiovascular events MASTER-DAPT Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation with an Abbreviated versus Standard DAPT Regimen MBF Myocardial blood flow MCE Myocardial contrast echocardiography MCS Mechanical circulatory support MFR Myocardial flow reserve mHealth Mobile device-based healthcare MI Myocardial infarction MIDCAB Minimally invasive direct coronary artery bypass MRA Mineralocorticoid receptor antagonist MRI Magnetic resonance imaging MRR Microvascular resistance reserve MVA Microvascular angina MVD Multivessel disease NNH Number needed to harm NNT Number needed to treat to prevent an adverse event NOBLE Nordic–Baltic–British Left Main Revascularisation Study NSTEMI Non-ST-segment elevation myocardial infarction NTG Nitroglycerine NYHA New York Heart Association OAC Oral anticoagulant OCT Optical coherence tomography OR Odds ratio ORBITA Objective Randomised Blinded Investigation with optimal medical Therapy of Angioplasty in stable angina ORBITA-COSMIC Coronary Sinus Reducer Objective Impact on Symptoms, MRI Ischaemia and Microvascular Resistance PAD Peripheral artery disease PAR Protease-activated receptor PARR-2 F-18-Fluorodeoxyglucose Positron Emission Tomography Imaging-Assisted Management of Patients with Severe Left Ventricular Dysfunction and Suspected Coronary Disease: a Randomized, Controlled Trial PCI Percutaneous coronary intervention PCSK9 Proprotein convertase subtilisin/kexin type 9 Pd/Pa Distal coronary pressure to aortic pressure ratio PDE-5 Phosphodiesterase-5 PEGASUS-TIMI 54 Prevention of Cardiovascular Events in Patients with Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin Thrombolysis In Myocardial Infarction PESA Progression of Early Subclinical Atherosclerosis PET Positron emission tomography PRECISE-DAPT PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent Dual AntiPlatelet Therapy PRECOMBAT Randomized Trial of Stents versus Bypass Surgery for Left Main Coronary Artery Disease (trial) PRIZE Precision Medicine with Zibotentan in Microvascular Angina PROM Patient-reported outcome measure PROMISE Prospective Multicenter Imaging Study for Evaluation of Chest Pain PTP Pre-test probability QFR Quantitative flow ratio QoL Quality of life R3F French FFR Registry RAAS Renin–angiotensin–aldosterone system RCT Randomized controlled trial REVIVED-BCIS2 Percutaneous Revascularization for Ischemic Left Ventricular Dysfunction RF-CL Risk-factor-weighted clinical likelihood RFR Relative flow reserve RIPCORD Routine Pressure Wire Assessment Influence Management Strategy at Coronary Angiography for Diagnosis of Chest Pain trial RR Relative risk RWTA Regional systolic wall-thickening abnormalities SAPT Single antiplatelet therapy SCORE2 Systematic Coronary Risk Estimation 2 SCORE2-OP Systematic Coronary Risk Estimation 2–Older Persons SCOT-HEART Scottish Computed Tomography of the Heart SELECT Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity SGLT2 Sodium–glucose cotransporter 2 SLE Systemic lupus erythematosus SPECT Single-photon emission computed tomography STEMI ST-segment elevation myocardial infarction STICH Surgical Treatment for Ischemic Heart Failure STS-PROM Society of Thoracic Surgeons Predicted Risk of Mortality SURMOUNT Efficacy and Safety of Tirzepatide Once Weekly in Participants Without Type 2 Diabetes Who Have Obesity or Are Overweight With Weight- Related Comorbidities: A Randomized, Double- Blind, Placebo-Controlled Trial SYNTAX SYNergy between PCI with TAXUS and Cardiac Surgery THEMIS The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study TID Transient ischaemic dilatation TIMI Thrombolysis In Myocardial Infarction Tx Thromboxane ESC Guidelines 3421 Downloaded from academic.oup.com/eurheartj/article/45/36/3415/7743115 by guest on 07 October 2026