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2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension Developed by the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). Endorsed by the International Society for Heart and Lung Transplantation (ISHLT) and the European Reference Network on rare respiratory diseases (ERN-LUNG). Authors/Task Force Members: Marc Humbert (France), Gabor Kovacs (Austria), Marius M. Hoeper (Germany), Roberto Badagliacca (Italy), Rolf M.F. Berger (Netherlands), Margarita Brida (Croatia), Jørn Carlsen (Denmark), Andrew J.S. Coats (United Kingdom), Pilar Escribano-Subias (Spain), Pisana Ferrari (Italy), Diogenes S. Ferreira (Brazil), Hossein Ardeschir Ghofrani (Germany), George Giannakoulas (Greece), David G. Kiely (United Kingdom), Eckhard Mayer (Germany), Gergely Meszaros (Hungary), Blin Nagavci (Germany), Karen M. Olsson (Germany), Joanna Pepke-Zaba (United Kingdom), Jennifer K. Quint (United Kingdom), Göran Rådegran (Sweden), Gerald Simonneau (France), Olivier Sitbon (France), Thomy Tonia (Switzerland), Mark Toshner (United Kingdom), Jean-Luc Vachiery (Belgium), Anton Vonk Noordegraaf (Netherlands), Marion Delcroix *† (ERS Chairperson) (Belgium), Stephan Rosenkranz *† (ESC Chairperson) (Germany), and ESC/ERS Scientific Document Group * Corresponding authors: Stephan Rosenkranz, Clinic III for Internal Medicine (Department of Cardiology, Pulmonology and Intensive Care Medicine), and Cologne Cardiovascular Research Center (CCRC), Heart Center at the University Hospital Cologne, Kerpener Str. 62, 50937 Köln, Germany. Tel.: +49-221-478-32356. Email: stephan.rosenkranz@ukkoeln.de; and Marion Delcroix, Clinical Department of Respiratory Diseases, Centre of Pulmonary Vascular Diseases, University Hospitals of Leuven, Herestraat 49, 3000 Leuven, Belgium. Tel.: +32 16 346813. Email: marion.delcroix@uzleuven.be † The two chairpersons contributed equally to the document and are joint corresponding authors. Author/Task Force Member affiliations are listed in author information. 1 Representing the Association for European Paediatric and Congenital Cardiology (AEPC) ESC Clinical Practice Guidelines (CPG) Committee: listed in the Appendix. ESC subspecialty communities having participated in the development of this document: Associations: Association of Cardiovascular Nursing & Allied Professions (ACNAP), European Association of Cardiovascular Imaging (EACVI), and Heart Failure Association (HFA). Councils: Council on Cardiovascular Genomics. Working Groups: Adult Congenital Heart Disease, Pulmonary Circulation and Right Ventricular Function, Thrombosis. Patient Forum The content of these European Society of Cardiology (ESC)/European Respiratory Society (ERS) Guidelines has been published for personal and educational use only. No commercial use is authorized. No part of the ESC/ERS Guidelines may be translated or reproduced in any form without written permission from the ESC and the ERS. Permission can be obtained upon submission of a written request to Oxford University Press, the publisher of the European Heart Journal, and the party authorized to handle such permissions on behalf of the ESC (journals. permissions@oup.com). European Heart Journal (2022) 43, 3618–3731 https://doi.org/10.1093/eurheartj/ehac237 Downloaded from academic.oup.com/eurheartj/article/43/38/3618/6673929 by guest on 07 October 2026