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160-179 140-159 120-139 100-119 160-179 140-159 120-139 100-119 160-179 140-159 120-139 100-119 160-179 140-159 120-139 100-119

160-179 140-159 120-139 100-119 160-179 140-159 120-139 100-119 160-179 140-159 120-139 100-119 160-179 140-159 120-139 100-119 160-179 140-159 120-139 100-119 160-179 140-159 120-139 100-119 85-89

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Systolic blood pressure (mmHg) 3.0-3.9 4.0-4.9 5.0-5.9 6.0-6.9 3.0-3.9 4.0-4.9 5.0-5.9 6.0-6.9 3.0-3.9 4.0-4.9 5.0-5.9 6.0-6.9 3.0-3.9 4.0-4.9 5.0-5.9 6.0-6.9

Non-smoking Smoking

Age (y) <50 years

<2.5% 2.5 to <7.5% ≥7.5% 50-69 years <5% 5 to <10% ≥10% ≥70 years

<7.5% 7.5 to <15% ≥15%

SCORE2 & SCORE2-OP 10-year risk of (fatal and non-fatal) CV events in populations at low CVD risk

Non-smoking Smoking

Non-HDL cholesterol

Women Men

SCORE2-OP

SCORE2 mmol/L

150 200 250 150 200 250 150 200 250 150 200 250 mg/dL

Figure 3 Systematic Coronary Risk Estimation 2 and Systematic Coronary Risk Estimation 2-Older Persons risk charts for fatal and non-fatal (myocardial infarction, stroke) cardiovascular disease.68,72 ASCVD = atherosclerotic cardiovascular disease; CV = cardiovascular; CVD = cardiovascular disease; SBP = systolic blood pressure; HDL-C = high-density lipoprotein cholesterol; SCORE2 = Systematic Coronary Risk Estimation 2; SCORE2-OP = Systematic Coronary Risk Estimation 2-Older Persons; TFYR = The Former Yugoslav Republic; UK = United Kingdom. For apparently healthy people aged 4069 years, the SCORE2 algorithm68 is used to estimate 10-year risk of fatal and non-fatal (myocardial infarction, stroke) CVD. For apparently healthy people >_70 years of age, the SCORE2-OP is used.72. Low-risk countries: Belgium, Denmark, France, Israel, Luxembourg, Norway, Spain, Switzerland, the Netherlands, and the UK. Moderate-risk countries: Austria, Cyprus, Finland, Germany, Greece, Iceland, Ireland, Italy, Malta, Portugal, San Marino, Slovenia, and Sweden. High-risk countries: Albania, Bosnia and Herzegovina, Croatia, Czech Republic, Estonia, Hungary, Kazakhstan, Poland, Slovakia, and Turkey. Very-high-risk countries: Algeria, Armenia, Azerbaijan, Belarus, Bulgaria, Egypt, Georgia, Kyrgyzstan, Latvia, Lebanon, Libya, Lithuania, Montenegro, Morocco, Republic of Moldova, Romania, Russian Federation, Serbia, Syria, TFYR (Macedonia), Tunisia, Ukraine, and Uzbekistan. Downloaded from academic.oup.com/eurheartj/article/42/34/3227/6358713 by guest on 07 October 2026