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............................................................................................................................................................................ LVEDP Left ventricular end-diastolic pressure LVEF Left ventricular ejection fraction LVESD Left ventricular end-systolic diameter LVH Left ventricular hypertrophy LVNC Left ventricular non-compaction LVOT Left ventricular outflow tract LVOTO Left ventricular outflow tract obstruction MADIT-CRT Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy (trial) MADIT-II Multicenter Automatic Defibrillator Implantation Trial II (trial) MADIT-RIT Multicenter Automatic Defibrillator Implantation Trial  Reduce Inappropriate Therapy (trial) MAGGIC Meta-Analysis Global Group in Chronic Heart Failure MCS Mechanical circulatory support MEK Mitogen-activated protein kinase MI Myocardial infarction MITRA-FR Percutaneous Repair with the MitraClip Device for Severe Functional/Secondary Mitral Regurgitation (trial) MMR Mismatch repair MR Mitral regurgitation MRA Mineralocorticoid receptor antagonist MRI Magnetic resonance imaging mRNA Messenger ribonucleic acid MR-proANP Mid-regional pro-atrial natriuretic peptide MT Medical therapy MV Mitral valve mWHO Modified World Health Organization MYPC Myosin-binding protein C NICM Non-ischaemic cardiomyopathy NKX2-5 NK2 transcription factor related, locus 5 NP Natriuretic peptide NSAID Non-steroidal anti-inflammatory drug NSVT Non-sustained ventricular tachycardia NT-proBNP N-terminal pro-B-type natriuretic peptide NYHA New York Heart Association o.d Omne in die (once daily) OMT Optimal medical therapy OSA Obstructive sleep apnoea PA Pulmonary artery PaO2 Partial pressure of oxygen PARADIGM-HF Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure (trial) pCO2 Partial pressure of carbon dioxide PCI Percutaneous coronary intervention PCR Polymerase chain reaction PCWP Pulmonary capillary wedge pressure PEP-CHF Perindopril in Elderly People with Chronic Heart Failure (trial) PET Positron emission tomography PKP2 Plakophilin 2 PLN Phospholamban PPCM Peripartum cardiomyopathy PREVEND Prevention of REnal and Vascular ENd-stage Disease (trial) PV Pulmonary vein PVC Premature ventricular contraction PVI Pulmonary vein isolation pVO2 Peak exercise oxygen consumption QI Quality indicator QOL Quality of life QRS Q, R, and S waves of an ECG RAAS Renin-angiotensin-aldosterone system RACE II Rate Control Efficacy in Permanent Atrial Fibrillation: a Comparison between Lenient versus Strict Rate Control II (trial) RAFT Resynchronization/Defibrillation for Ambulatory Heart Failure Trial (trial) RASi Renin-angiotensin system inhibitor RATE-AF Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (trial) RBM20 Ribonucleic acid binding motif 20 RCT Randomized controlled trial REMATCH Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (trial) REVERSE REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction (trial) REVIVED REVascularization for Ischaemic VEntricular Dysfunction (trial) RNA Ribonucleic acid RRT Renal replacement therapy RV Right ventricular/ventricle RVAD Right ventricular assist device RVEDP Right ventricular end-diastolic pressure SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 SAVR Surgical aortic valve replacement SBP Systolic blood pressure SCORED Effect of Sotagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk (trial) SCN5a Sodium channel alpha subunit 5 SENIORS Study of the Effects of Nebivolol Intervention on Outcomes and Rehospitalizations in Seniors with Heart Failure (trial) SERVE-HF Treatment of Sleep-Disordered Breathing with Predominant Central Sleep Apnea by Adaptive Servo Ventilation in Patients with Heart Failure (trial) SGLT2 Sodium-glucose co-transporter 2 S-ICD Subcutaneous implantable cardioverterdefibrillator SMR Secondary mitral regurgitation SPECT Single-photon emission computed tomography Downloaded from academic.oup.com/eurheartj/article/42/36/3599/6358045 by guest on 07 October 2026