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Figure 6 Central Illustration. Risk-adjusted management strategy for acute pulmonary embolism. CTPA= computed tomography pulmonary angiography/angiogram; PE = pulmonary embolism; PESI = Pulmonary Embolism Severity Index; RV = right ventricular; sPESI = simplified Pulmonary Embolism Severity Index; TTE= transthoracic echocardiogram. aSee also emergency management algorithm shown in the online Supplementary Data. bRefer to Table 8 for definition of high, intermediate-high-, intermediate-low-, and low-risk PE. cCancer, heart failure and chronic lung disease are included in the PESI and sPESI (Table 7). dSee Supplementary Data Table 12 for the Hestia criteria. ePrognostically relevant imaging (TTE or CTPA) findings in patients with acute PE, are graphically presented in Figure 3. fA cardiac troponin test may already have been performed during initial diagnostic work-up. gIncluded in the Hestia criteria. Downloaded from academic.oup.com/eurheartj/article/41/4/543/5556136 by guest on 07 October 2026