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Evaluating strict and con- ventional left bundle branch block criteria using electrocardiographic simulations. Europace. 2013;15:1816–21. 3 CLINICAL MANIFESTATION OF BRADYCARDIA AND CONDUCTION DISORDERS 3.1 Clinical Manifestations of Bradycardia S3.1-1. Brubaker PH, Kitzman DW. Chronotropic incompetence: causes, consequences, and management. Circulation. 2011;123:1010–20. S3.1-2. Barold SS, Hayes DL. Second-degree atrioventricular block: a reappraisal. Mayo Clin Proc. 2001;76:44–57. S3.1-3. Epstein AE, DiMarco JP, Ellenbogen KA, et al. 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. Circulation. 2012;127:e283–352. S3.1-4. Goldschlager N. Underlying assumptions in evaluating “symptom- atic bradycardia” (or, are we asking the right questions?). 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