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CLINICAL STATEMENTS AND GUIDELINES

Circulation. 2025;152:e114–e218. DOI: 10.1161/CIR.0000000000001356 September 16, 2025 e187

Other considerations relate to the management of patients with severe hypertension accompanied by symptoms and signs of acute CVD events and to man­ agement of hypertension during the perioperative period. Trials are challenging in these areas, and pragmatic study designs may be helpful.

PEER REVIEW COMMITTEE MEMBERS

Donna K. Arnett, BSN, MSPH, PhD, FAHA Co-Chair; Eugene Yang, MD, MS, FACC, Co-Chair; David Aguilar, MD, MSc, FAHA, FACC; Vivek Bhalla, MD, FAHA; Sarah J. Billups, PharmD, BCPS*; Margaret Bowers, DNP, FNP-BC, FACC*; Beverly B. Green, MD, MPH, FAHA; Steven M. Greenberg, MD, PhD, FAHA; Eileen Handberg, ANP-BC, PhD, FAHA, FACC, FPCNA*; Christopher D. Jackson, MD, FACP*; Wallace Robert Johnson Jr, MD*; Min Ji Kwak, MD, MS, DrPH*; Renee Langstaff, DMSc, MSPAS, PA-C*; Carlos Jose Rodriguez, MD, MPH; Mark K. Santillan, MD, PhD, FAHA; Michael D. Shapiro, DO, MCR, FAHA, FACC, FASPC*; Prentiss Taylor, MD, FACP, FACPM*; Jennifer T. Thibodeau, MD, MSCS, FACC, FAHA; Gregory Wozniak, PhD*; Jackson T. Wright Jr, MD, PhD, FAHA*; Wendy C. Ziai, MD, MPH, FAHA

ACC/AHA JOINT COMMITTEE ON CLINICAL PRACTICE GUIDELINES

Catherine M. Otto, MD, FACC, FAHA, Chair; Sunil V. Rao, MD, FACC, FSCAI, Chair Elect; Joshua A. Beckman, MD, MS, FAHA, FACC, Immediate Past-Chair*; Anastasia Armbruster, PharmD, FACC*; Vanessa Blumer, MD; Leslie L. Davis, PhD, ANP-BC, FACC, FAHA; Dave L. Dixon, PharmD, FACC, FAHA, BCACP, CLS; Victor A. Ferrari, MD, FACC, FAHA, FASE, MSCMR; Stephen E. Fremes, MD, FACC; Mario F. L. Gaudino, MD, PhD, MSCE, FEBCTS, FACC, FAHA; Heather M. Johnson, MD, MS, FAHA, FACC, FASPC*; Hani Jneid, MD, FACC, FAHA, FSCAI; William Schuyler Jones, MD, FACC; Sadiya S. Khan, MD, MSc, FACC, FAHA; Prateeti Khazanie, MD, MPH, FAHA*; Michelle Maya Kittleson, MD, PhD, FACC, FAHA*; Venugopal Menon, MD, FACC, FAHA, FESC; Debabrata Mukherjee, MD, MS, FACC, FAHA, MSCAI*; Daniel Munoz, MD, MPA; Tanveer Rab, MD, FACC*; Garima Sharma, MBBS, FACC; Daichi Shimbo, MD; Jacqueline Tamis-Holland, MD, FACC*; Joseph Woo, MD, FACS, FACC, FAHA; Boback Ziaeian, MD, PhD, FACC, FAHA*

PRESIDENTS AND STAFF

American College of Cardiology

Christopher M. Kramer, MD, FACC, President Cathleen C. Gates, Chief Executive Officer Richard J. Kovacs, MD, MACC, Chief Medical Adviser Justine Varieur Turco, MA, Divisional Vice President, Sci­

entific Publications & Guidelines Mindy J. Saraco, MHA, Director, Clinical Policy and

Guidelines Grace D. Ronan, Senior Production and Operations Man­

ager, Clinical Policy Publications Leah Patterson, Project Manager, Clinical Content

American College of Cardiology/American Heart Association

Thomas S.D. Getchius, National Senior Director, Guidelines Abdul R. Abdullah, MD, Director, Guideline Science and

Methodology Sabrina Singleton-Times, DHSc, MPH Shae Martinez, MLS, Reference Consultant, Medical

Librarian

American Heart Association

Keith Churchwell, MD, FAHA, President Nancy Brown, Chief Executive Officer Mariell Jessup, MD, FAHA, Chief Science and Medical

Officer Nicole Aiello Sapio, EdD, Executive Vice President, Office

of Science Strategies and Operations Radhika Rajgopal Singh, PhD, Senior Vice President,

Office of Science and Medicine Prashant Nedungadi, BPharm, PhD, National Vice Presi­

dent, Science and Medicine, Clinical Guidelines Maggie Eaton, PhD, RN, Science and Medicine Advisor Joseph W. Loftin III, National Director, Statements and

Guidelines

ARTICLE INFORMATION

This document was approved by the American College of Cardiology Clinical Policy Approval Committee and the American Heart Association Science Advi­ sory and Coordinating Committee in April 2025, and the American College of Cardiology Science and Quality Committee and the American Heart Association Executive Committee in May 2025. Supplemental materials are available with this article at https://www.ahajour­ nals.org/doi/suppl/10.1161/CIR.0000000000001356 This article has been copublished in Hypertension and Journal of the American College of Cardiology. Copies: This document is available on the websites of the American Heart Association (professional.heart.org) and the American College of Cardiology (www. acc.org). A copy of the document is also available at https://professional.heart.org/ statements by selecting the “Guidelines & Statements” button. To purchase addi­ tional reprints, call 215-356-2721 or email Meredith.Edelman@wolterskluwer.com. The expert peer review of AHA-commissioned documents (eg, scientific statements, clinical practice guidelines, systematic reviews) is conducted by the AHA Office of Science Operations. For more on AHA statements and guidelines development, visit https://professional.heart.org/statements. Select the “Guide­ lines & Statements” drop-down menu near the top of the webpage, then click “Publication Development.”

Permissions: Multiple copies, modification, alteration, enhancement, and dis­ tribution of this document are not permitted without the express permission of the American Heart Association. Instructions for obtaining permission are located at https://www.heart.org/permissions. A link to the “Copyright Permissions Request Form” appears in the second paragraph (https://www.heart.org/en/about-us/ statements-and-policies/copyright-request-form). *Former Task Force member; current member during the writing effort.

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