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CLINICAL STATEMENTS AND GUIDELINES August 29, 2023 Circulation. 2023;148:e9–e119. DOI: 10.1161/CIR.0000000000001168 Virani et al 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Chronic Coronary Disease Guideline high-quality research is needed to examine whether preventative strategies—such as indoor air purifiers and N95 masks during periods of substantial wildfire smoke exposure or public spaces with airconditioning during extreme heat—are protective in patients with CCD who are at increased risk of cardiovascular events. • Research is needed to explore how to best integrate SDOH into electronic health records to enable practitioners to coordinate care for patients with CCD challenged with health inequities. • Although some electronic health records allow estimation of patient out-of-pocket costs for medications, testing, and treatments, more work is needed in development and dissemination of tools to allow clinicians to determine patient costs accurately at the point of care. • Research is needed to determine whether GDMT is associated with improved outcomes in older adults with CCD or patients with CCD on hemodialysis. • Studies are needed to assess which interventions lead to effective guideline implementation in clinical practice. Similarly, research is needed to assess the effect of a new guideline release at the patient, clinic, hospital, health care systems, and the community levels. PEER REVIEW COMMITTEE MEMBERS H. Vernon Anderson, MD, FAHA, FACC, Chair*; Sunil V. Rao, MD, FACC, Vice Chair*; Columbus Batiste II, MD, FACC; Roger Blumenthal, MD, FAHA, FACC; Matthew A. Cavender, MD, MPH, FACC; Anne Carol Goldberg, MD, FNLA, FAHA†; Cynthia Jackevicius, BScPhm, PharmD, MSc, BCPS, BCCP, FAHA, FACC, FCCP‡; Friederike K. Keating, MD, FACC; Thomas S. Metkus, MD, PhD, FACC; Leslee J. Shaw, PhD, FACC, FAHA; Chloe D. Villavaso, MN, APRN, FPCNA, AACC§; Brittany A. Zwischenberger, MD, MHS AHA/ACC JOINT COMMITTEE ON CLINICAL PRACTICE GUIDELINES Joshua A. Beckman, MD, MS, FAHA, FACC, Chair; Catherine M. Otto, MD, FACC, FAHA, Chair-Elect; Patrick T. O’Gara, MD, MACC, FAHA, Immediate Past Chair||; Anastasia Armbruster, PharmD, FACC; Kim K. Birtcher, PharmD, MS, AACC||; Leslie L. Davis, PhD, ANP-BC, FACC, FAHA, FPCNA; Lisa de las Fuentes, MD, MS, FAHA; Anita Deswal, MD, MPH, FACC, FAHA; Dave L. Dixon, PharmD, FAHA, FACC, FCCP, FNLA||; Victor A. Ferrari, MD, FACC, FAHA; Bulent Gorenek, MD, FACC||; Norrisa Haynes, MD, MPH||; Adrian F. Hernandez, MD, FAHA; José A. Joglar, MD, FAHA, FACC||; Heather M. Johnson, MD, MS, FAHA, FACC, FASPC; W. Schuyler Jones, MD, FACC; Prateeti Khazanie, MD; Michelle Kittleson, MD, PhD, FAHA; Daniel B. Mark, MD, MPH, FACC||; Debabrata Mukherjee, MD, FACC, FAHA, FSCAI; Latha Palaniappan, MD, MS, FAHA, FACC||; Mariann R. Piano, RN, PhD, FAHA||; Tanveer Rab, MD, FACC; Erica S. Spatz, MD, MHS, FACC||; Jacqueline E. Tamis-Holland, MD, FACC, FAHA; Y. Joseph Woo, MD, FACC, FAHA; Boback Ziaeian, MD, PhD, FAHA PRESIDENTS AND STAFF American College of Cardiology B. Hadley Wilson, MD, FACC, President Cathleen C. Gates, Chief Executive Officer Richard J. Kovacs, MD, MACC, Chief Medical Adviser MaryAnne Elma, MPH, Senior Director, Enterprise Content and Digital Strategy Grace D. Ronan, Team Leader, Clinical Policy Publications Leah Patterson, Project Manager, Clinical Content Development American College of Cardiology/American Heart Association Thomas S.D. Getchius, National Senior Director, Guidelines Abdul R. Abdullah, MD, Director, Guideline Science and Methodology American Heart Association Michelle A. Albert, MD, MPH, FAHA, President Nancy Brown, Chief Executive Officer Mariell Jessup, MD, FAHA, Chief Science and Medical Officer Radhika Rajgopal Singh, PhD, Senior Vice President, Office of Science and Medicine Prashant Nedungadi, BPharm, PhD, Vice President, Science and Medicine, Clinical Guidelines Jody Hundley, Senior Production and Operations Man- ager, Scientific Publications, Office of Science Operations ARTICLE INFORMATION This document was approved by the American College of Cardiology Clinical Policy Approval Committee and the American Heart Association Science Advisory and Coordinating Committee in January 2023, and the American College of Cardiology Science and Quality Committee and the American Heart Association Executive Committee in April 2023. Supplemental Materials are available with this article at https://www.ahajournals. org/doi/suppl/10.1161/CIR.0000000000001168 *ACC/AHA representative. †National Lipid Association representative. ‡American College of Clinical Pharmacy representative. §Preventive Cardiovascular Nurses Association representative. ||Former Joint Committee on Clinical Practice Guideline member; current member during the writing effort. ||Former Joint Committee on Clinical Practice Guideline member; current member during the writing effort. Downloaded from http://ahajournals.org by on October 7, 2026